Publications in scientific journals: 2015

Research based on NTR data

2015

Abdellaoui A, Ehli EA, Hottenga JJ, Weber Z, Mbarek H, Willemsen G, Beijsterveldt CEM van, Brooks A, Hudziak JJ, Sullivan PF, Geus EJC de, Davies GE, Boomsma DI. CNV Concordance in 1,097 MZ Twin Pairs. Twin Research and Human Genetics. 2015;18(01):1-12
DOI: 10.1017/thg.2014.86

Abdellaoui A, Hottenga JJ, Willemsen G, Bartels M, Beijsterveldt CEM van, Ehli EA, Davies GE, Brooks A, Sullivan PF, Penninx BWJH, Geus EJC de, Boomsma DI. Educational Attainment Influences Levels of Homozygosity through Migration and Assortative Mating. PLOS ONE. 2015;e0118935, Open Access
DOI: 10.1371/journal.pone.0118935

Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Drabant Conley E, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Boomsma DI, Penninx BWJH, Geus EJC de, Hottenga JJ, Middeldorp CM, Willemsen G, Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron. 2015;86(5):1189-1202, Open Access
DOI: 10.1016/j.neuron.2015.05.034
Supplementary Materials (zip file)

Bartels M. Genetics of Wellbeing and Its Components Satisfaction with Life, Happiness, and Quality of Life: A Review and Meta-analysis of Heritability Studies. Behavior Genetics. 2015;45(2):137-156, Open Access
DOI: 10.1007/s10519-015-9713-y

Baselmans BML, Dongen J van, Nivard MG, Lin BD, BIOS Consortium, Zilhão NR, Boomsma DI, Bartels M. Epigenome-Wide Association Study of Wellbeing. Twin Research and Human Genetics. 2015;18(6):710-719
DOI: 10.1017/thg.2015.85
Supplementary Materials (zip file)

Beek JHDA van, Lubke GH, Moor MHM de, Willemsen G, Geus EJC de, Hottenga JJ, LivGen consortium, Walters RK, Smit JH, Penninx BWJH, Boomsma DI. Heritability of liver enzyme levels estimated from genome-wide SNP data. European Journal of Human Genetics. 2015;23(9):1223-1228
DOI: 10.1038/ejhg.2014.259
Supplementary Materials (zip file)

Boomsma DI. Aggression in children: unravelling the interplay of genes and environment through (epi)genetics and metabolomics. Journal of Pediatric and Neonatal Individualized Medicine. 2015;4(2):e040251, Open Access
DOI: 10.7363/040251

Bootsman F, Brouwer RM, Kemner SM, Schnack HG, Schot AC van der, Vonk R, Hillegers MHJ, Boomsma DI, Hulshoff Pol HE, Nolen WA, Kahn RS, Haren NEM van. Contribution of genes and unique environment to cross-sectional and longitudinal measures of subcortical volumes in bipolar disorder. European Neuropsychopharmacology. 2015;25(12):2197-2209
DOI: 10.1016/j.euroneuro.2015.09.023
Supplementary Materials (zip file)

Brouwer RM, Koenis MMG, Schnack HG, Baal GC van, Soelen ILC van, Boomsma DI, Hulshoff Pol HE. Longitudinal Development of Hormone Levels and Grey Matter Density in 9 and 12-Year-Old Twins. Behavior Genetics. 2015;45(3):313-323, Open Access
DOI: 10.1007/s10519-015-9708-8
Supplementary Materials (zip file)

Cacioppo JT, Cacioppo S, Cole SW, Capitanio JP, Goossens L, Boomsma DI. Loneliness Across Phylogeny and a Call for Comparative Studies and Animal Models. Perspectives on Psychological Science. 2015;10(2):202-212
DOI: 10.1177/1745691614564876

The Coffee and Caffeine Genetics Consortium, Cornelis MC, Byrne EM, Esko T, Nalls MA, Ganna A, Paynter N, Monda KL, Amin N, Fischer K, Renstrom F, Vink JM, Treur JL, Hottenga JJ, International Parkinson's Disease Genomics Consortium, North American Brain Expression Consortium, UK Brain Expression Consortium, Boomsma DI, Franks PW, Ridker PM, Duijn CM van, Heiss G, Metspalu A, North KE, Ingelsson E, Nettleton JA, Dam RM van, Chasman DI. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry. 2015;20(5):647-656
DOI: 10.1038/mp.2014.107
Supplementary Materials (zip file)

Davies MN, Verdi S, Burri A, Trzaskowski M, Lee M, Hettema JM, Jansen R, Boomsma DI, Spector TD. Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression. PLOS ONE. 201510(8):e0134865, Open Access
DOI: 10.1371/journal.pone.0134865
Supplementary Materials (zip file)

Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Hottenga JJ, Martin NG, Neale BM, Willemsen G, Boomsma DI, Montgomery GW, Spector TD, van Duijn CM, Metspalu A, Uitterlinden AG, The PRACTICAL Consortium, kConFab Investigators, AOCS Investigators, Generation Scotland, EPIC-InterAct Consortium, LifeLines Cohort Study, Price AL, Stefansson K, Visser JA, Ong KK, Chang-Claude J, Murabito JM, Perry JRB, Murray A, many others. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nature Genetics. 2015;47(11):1294-1303
DOI: 10.1038/ng.3412
Supplementary Materials (zip file)

Dolan CV, Nivard MG, Dongen J van, Sluis S van der, Boomsma DI. Methylation as an epigenetic source of random genetic effects in the classical twin design. Advances in Genomics and Genetics. 2015;5:305-315, Open Access
DOI: 10.2147/AGG.S46909

Dongen J van, Willemsen G, Heijmans BT, Neuteboom J, Kluft C, Jansen R, Penninx BWJH, Slagboom PE, Geus EJC de, Boomsma DI. Longitudinal weight differences, gene expression, and blood biomarkers in BMI discordant identical twins. International Journal of Obesity. 2015;39(6):899-909
DOI: 10.1038/ijo.2015.24

Dongen J van, Nivard MG, Baselmans BML, Zilhão NR, Ligthart L, BIOS Consortium, Heijmans BT, Bartels M, Boomsma DI. Epigenome-Wide Association Study of Aggressive Behavior. Twin Research and Human Genetics. 2015;18(06):686-698
DOI: 10.1017/thg.2015.74
Supplementary Materials (zip file)

Draisma HHM, Pool R, Kobl M, Jansen R, Petersen AK, Vaarhorst AAM, Yet I, Haller T, Demirkan A, Esko T, Geus EJC de, Hottenga JJ, Willemsen G, Ommen GJB van, Illig T, Bell JT, Mangino M, Suhre K, McCarthy MI, Gieger C, Isaacs A, Duijn CM van, Boomsma DI, others. Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications. 2015;6:7208
DOI: 10.1038/ncomms8208
Supplementary Materials (zip file)

Estourgie-Van Burk GF, Bartels M, Boomsma DI. A Twin-Sibling Study on Early Growth and Hormone Levels in Adolescents. Behavior Genetics. 2015;45(3):283-293
DOI: 10.1007/s10519-014-9697-z

Fall T, Hägg S, Ploner A, Mägi R, Fischer K, Draisma HHM, Sarin AP, Benyamin B, Ladenvall C, Åkerlund M, Penninx BWJH, Boomsma DI, Järvelin MR, Lyssenko V, Metspalu A, Strachan DP, Salomaa V, Ripatti S, Pedersen NL, Prokopenko I, McCarthy MI, Ingelsson E, many others on behalf of the ENGAGE Consortium. Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors. Diabetes. 2015;64(5):1841-1852
DOI: 10.2337/db14-0988
Supplementary Materials (zip file)

Fedko IO, Hottenga JJ, Medina-Gomez C, Pappa I, Beijsterveldt CEM van, Ehli EA, Davies GE, Rivadeneira F, Tiemeier H, Swertz MA, Middeldorp CM, Bartels M, Boomsma DI. Estimation of Genetic Relationships Between Individuals Across Cohorts and Platforms: Application to Childhood Height. Behavior Genetics. 2015;45(5):514-528, Open Access
DOI: 10.1007/s10519-015-9725-7

Francioli LC, Polak PP, Koren A, Menelaou A, Chun S, Renkens I, Genome of the Netherlands Consortium, Duijn CM van, Swertz MA, Wijmenga C, Ommen GJ van, Slagboom PE, Boomsma DI, Ye K, Guryev V, Arndt PF, Kloosterman WP, Bakker PIW de, Sunyaev SR. Genome-wide patterns and properties of de novo mutations in humans. Nature Genetics. 2015;47(7):822-826
DOI: 10.1038/ng.3292
Supplementary Materials (zip file)

Franic S, Dolan CV, Broxholme J, Hu H, Zemojtel T, Davies GE, Nelson KA, Ehli EA, Pool R. Mendelian and polygenic inheritance of intelligence: A common set of causal genes? Using next-generation sequencing to examine the effects of 168 intellectual disability genes on normal-range intelligence. Intelligence. 2015;49:10-22
DOI: 10.1016/j.intell.2014.12.001
Supplementary Materials (zip file)

Franic S, Groen-Blokhuis MM, Dolan CV, Kattenberg MV, Pool R, Xiao X, Scheet PA, Ehli EA, Davies GE, Sluis S van der, Abdellaoui A, Hansell NK, Martin NG, Hudziak JJ, Beijsterveldt CEM van, Swagerman SC, Hulshoff Pol HE, Geus EJC de, Bartels M, Ropers HH, Hottenga JJ, Boomsma DI. Intelligence: shared genetic basis between Mendelian disorders and a polygenic trait. European Journal of Human Genetics. 2015;23(10):1378-1383
DOI: 10.1038/ejhg.2015.3
Supplementary Materials (zip file)

Genetics of Personality Consortium, Moor MHM de, Berg SM van den, Verweij KJ, Krueger RF, Luciano M, Arias Vasquez A, Matteson LK, Derringer J, Esko T, Amin N, Fedko IO, Hottenga JJ, Milaneschi Y, Ouwens KG, Grabe HJ, Duijn CM van, Evans DM, Schlessinger D, Pedersen NL, Terracciano A, McGue M, Penninx BWJH, Martin NG, Boomsma DI, many others. Meta-analysis of Genome-wide Association Studies for Neuroticism, and the Polygenic Association With Major Depressive Disorder. JAMA Psychiatry. 2015;72(7):642-650, Open Access
DOI: 10.1001/jamapsychiatry.2015.0554
www.tweelingenregister.org/gpc
Supplementary Materials (zip file)

Goossens L, Roekel E van, Verhagen M, Cacioppo JT, Cacioppo S, Maes M, Boomsma DI. The Genetics of Loneliness: Linking Evolutionary Theory to Genome-Wide Genetics, Epigenetics, and Social Science. Perspectives on Psychological Science. 2015;10(2):213-226
DOI: 10.1177/1745691614564878

Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, Vink JM, Hottenga JJ, Willemsen G, Boomsma DI, O’Connor GT, Stone KL, Tanaka T, Viikari J, Gharib SA, Punjabi NM, Räikkönen K, Völzke H, Mignot E, Tiemeier H, many others. Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study. Molecular Psychiatry. 2015;20(10):1232-1239
DOI: 10.1038/mp.2014.133
Supplementary Materials (zip file)

Hägg S, Fall T, Ploner A, Mägi R, Fischer K, Draisma HHM, Kals M, Vries PS de, Dehghan A, Willems SM, Kuulasmaa K, Magnusson PK, Esko T, Hofman A, Geus EJC de, Lind L, Giedraitis V, Perola M, Evans A, Ferrières J, Virtamo J, Kee F, Trégouët DA, Arveiler D, Amouyel P, Gianfagna F, Brambilla P, Ripatti S, Duijn CM van, Metspalu A, Prokopenko I, McCarthy MI, Pedersen NL, Ingelsson E, the European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium. Adiposity as a cause of cardiovascular disease: a Mendelian randomization study. International Journal of Epidemiology. 2015;44(2):578-586, Open Access
DOI: 10.1093/ije/dyv094
Supplementary Materials (zip file)

Hansell NK, Halford GS, Andrews G, Shum DHK, Harris SE, Davies G, Franic S, Christoforou A, Zietsch B, Painter J, Medland SE, Ehli EA, Davies GE, Steen VM, Lundervold AJ, Reinvang I, Montgomery GW, Espeseth T, Hulshoff Pol HE, Starr JM, Martin NG, Hellard S Le, Boomsma DI, Deary IJ, Wright MJ. Genetic Basis of a Cognitive Complexity Metric. PLOS ONE. 2015;10(4), Open Access
DOI: 10.1371/journal.pone.0123886
Supplementary Materials (zip file)

Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivieres S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, den Braber A, Milaneschi Y, Fedko IO, Hottenga JJ, Montgomery GW, van ‘t Ent D, Davies GE, Kahn RS, Penninx BWJH, Boomsma DI, Brouwer RM, Hulshoff Pol HE, Van Duijn CM, Bis JC, The Alzheimer’s Disease Neuroimaging Initiative, The CHARGE Consortium, EPIGEN, IMAGEN, SYS, Martin NG, Wright MJ, Schumann G, Franke B, Thompson PM, Medland SE, many others. Common genetic variants influence human subcortical brain structures. Nature. 2015;520(7546):224-229
DOI: 10.1038/nature14101
Supplementary Materials (zip file)

Horikoshi M, Mägi R, Bunt M van de, Surakka I, Sarin AP, Mahajan A, Marullo L, Thorleifsson G, Hägg S, Hottenga JJ, Willemsen G, Milaneschi Y, Leeuwen EM van, Slagboom PE, Van Duijn CM, Penninx BWJH, Geus EJC de, Smit JH, Boomsma DI, Pedersen NL, Ingelsson E, Thorsteinsdottir U, Stefansson K, Ripatti S, Prokopenko I, McCarthy MI, Morris AP, ENGAGE Consortium. Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation. PLOS GENETICS. 2015;11(7):e1005230, Open Access
DOI: 10.1371/journal.pgen.1005230
Supplementary Materials (zip file)

Houtem CMHH van, Wijk AJ van, Boomsma DI, Ligthart L, Visscher CM, Jongh A de. Self-reported gagging in dentistry: prevalence, psycho-social correlates and oral health. Journal of Oral Rehabilitation. 2015;42(7):487-494
DOI: 10.1111/joor.12289

Huppertz C, Bartels M, Beijsterveldt CEM van, Willemsen G, Hudziak JJ, Geus EJC de. Regular exercise behaviour in youth is not related to current body mass index or body mass index at 7-year follow-up. Obesity Science & Practice. 2015;1(1):1-11, Open Access
DOI: 10.1002/osp4.2

Jacobsen KK, Nievergelt CM, Zayats T, Greenwood TA, Anttila V, Akiskal HS, BiGS Consortium, IHG Consortium, Ligthart L, Hottenga JJ, Vink JM, Penninx BWJH, Boomsma DI, Haavik J, Bernt Fasmer O, Kelsoe JR, Johansson S, Oedegaard KJ, others. Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder. Journal of Affective Disorders. 2015;172:453-461, Open Access
DOI: 10.1016/j.jad.2014.10.004
Supplementary Materials (zip file)

Jelenkovic A, Yokoyama Y, Sund R, Honda C, Bogl LH, Aaltonen S, Ji F, Ning F, Pang Z, Ordonana JR, Bartels M, Beijsterveldt CEM van, Harris JR, Willemsen G, Busjahn A, Goldberg JH, Rasmussen F, Hur YM, Boomsma DI, Sorensen TIA, Kaprio J, Silventoinen K, many others. Zygosity Differences in Height and Body Mass Index of Twins From Infancy to Old Age: A Study of the CODATwins Project. Twin Research and Human Genetics. 2015;18(05):557-570
DOI: 10.1017/thg.2015.57

Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C, Smith AV, Zhang W, Abdellaoui A, Hottenga JJ, Willemsen G, Boomsma DI, Gudnason V, Takahashi A, Chambers JC, Kooner JS, Strachan DP, Campbell H, Hirschhorn JN, Perola M, Polasek O, Wilson JF, others. Directional dominance on stature and cognition in diverse human populations. Nature. 2015;523(7561):459-462
DOI: 10.1038/nature14618
Supplementary Materials (zip file)

Kendler KS, Aggen SH, Li Y, Lewis CM, Breen G, Boomsma DI, Bot M, Penninx BWJH, Flint J. The similarity of the structure of DSM-IV criteria for major depression in depressed women from China, the United States and Europe. Psychological Medicine. 2015;45(09):1945-1954, Open Access
DOI: 10.1017/S0033291714003067

Kloosterman WP, Francioli LC, Hormozdiari F, Marschall T, Hehir-Kwa JY, Abdellaoui A, Lameijer EW, Moed MH, Koval V, Renkens I, Roosmalen MJ van, Arp P, Karssen LC, Coe BP, Handsaker RE, Suchiman ED, Cuppen E, Thung DT, McVey M, Wendl MC, Uitterlinden AG, Van Duijn CM, Swertz MA, Wijmenga C, Ommen G van, Slagboom PE, Boomsma DI, Schönhuth A, Eichler EE, Bakker PIW de, Ye K, Guryev V. Characteristics of de novo structural changes in the human genome. Genome Research. 2015;5(6):792-801, Open Access
DOI: 10.1101/gr.185041.114
Supplementary Materials (zip file)

Kochunov P, Jahanshad N, Marcus D, Winkler A, Sprooten E, Nichols TE, Wright SN, Hong LE, Patel B, Behrens T, den Braber A, Boomsma DI, Geus EJC de, Hariri A, van ‘t Ent D, Bastin ME, McIntosh A, Deary IJ, Hulshoff Pol HE, Blangero J, Thompson PM, Glahn DC, Essen DC van, others. Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data. NeuroImage. 2015;111:300-311
DOI: 10.1016/j.neuroimage.2015.02.050
Supplementary Materials (zip file)

Koenis MMG, Brouwer RM, Heuvel MP van den, Mandl RCW, Soelen ILC van, Kahn RS, Boomsma DI, Hulshoff Pol HE. Development of the brain's structural network efficiency in early adolescence: A longitudinal DTI twin study. Human Brain Mapping. 2015;36(12):4938-4953, Open Access
DOI: 10.1002/hbm.22988
Supplementary Materials (zip file)

Laurin CA, Hottenga JJ, Willemsen G, Boomsma DI, Lubke GH. Genetic Analyses Benefit From Using Less Heterogeneous Phenotypes: An Illustration With the Hospital Anxiety and Depression Scale (HADS). Genetic Epidemiology. 2015;39(4):317-324
DOI: 10.1002/gepi.21897
Supplementary Materials (zip file)

Leeuwen EM van, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, Willemsen G, Geus EJC de, Milaneschi Y, Penninx BWJH, The Genome of the Netherlands Consortium, Sijbrands EJ, Hottenga JJ, Uitterlinden AG, Swertz MA, Ommen GJB van, Bakker PIW de, Slagboom PE, Boomsma DI, Wijmenga C, Van Duijn CM, many others. Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications. 2015;6(6065), Open Access
DOI: 10.1038/ncomms7065
Supplementary Materials (zip file)

Leeuwen EM van, Kanterakis A, Deelen P, Kattenberg MV, The Genome of the Netherlands Consortium, Slagboom PE, Bakker PIW de, Wijmenga C, Swertz MA, Boomsma DI, Van Duijn CM, Karssen LC, Hottenga JJ. Population-specific genotype imputations using minimac or IMPUTE2. Nature Protocols. 2015;10(9):1285-1296
DOI: 10.1038/nprot.2015.077
Supplementary Materials (zip file)

Leeuwen EM van, HuffmanJE, Bis JC, Isaacs A, Mulder M, Sabo A, Smith AV, Demissie S, Manichaikul A, Brody JA, Mbarek H, Willemsen G, Geus EJC de, Milaneschi Y, Penninx BWJH, Oldehinkel AJ, Snieder H, Slagboom PE, Hottenga JJ, Boomsma DI, Morrison AC, Borecki IB, Rich SS, Padmanabhan S, Psaty BM, Rotter JI, Smith BH, Boerwinkle E, Cupples LA, Van Duijn CM, many others. Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C. npj Aging and Mechanisms of Disease. 2015;1(15011), Open Access
DOI: 10.1038/npjamd.2015.11
Supplementary Materials (zip file)

Lien R van, Neijts M, Willemsen G, Geus EJC de. Ambulatory measurement of the ECG T-wave amplitude. Psychophysiology. 2015;52(2):225-237, Open Access
DOI: 10.1111/psyp.12300

Lin BD, Mbarek H, Willemsen G, Dolan CV, Fedko IO, Abdellaoui A, Geus EJC de, Boomsma DI, Hottenga JJ. Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample. Genes. 2015;6(3):559-576, Open Access
DOI: 10.3390/genes6030559
Supplementary Materials (zip file)

Linneberg A, Jacobsen RK, Skaaby T, Taylor AE, Fluharty ME, Jeppesen JL, Bjorngaard JH, Åsvold BO, Gabrielsen ME, Campbell A, Mbarek H, Geus EJC de, Vink JM, Boomsma DI, Smith BH, Hayward C, Sørensen TIA, Thuesen BH, Sattar N, Morris RW, Romundstad PR, Munafò MR, Jarvelin MR, Husemoen LLN, others. Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomisation Meta-Analysis in the CARTA Consortium. Circulation: Cardiovascular Genetics. 2015;8(6):832-841, Open Access
DOI: 10.1161/CIRCGENETICS.115.001225
Supplementary Materials (zip file)

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, Helmer Q, Hottenga JJ, Vinkhuyzen AAE, Willemsen G, Slagboom PE, Snieder H, Uitterlinden AG, Van Duijn CM, Visscher PM, Beckmann JS, Barroso I, North KE, Ingelsson E, Hirschhorn JN, Loos RJF, Speliotes EK, Boomsma DI, Geus EJC de, Vink JM, many others. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206
DOI: 10.1038/nature14177
Supplementary Materials (zip file)

Loehlin JC, Bartels M, Boomsma DI, D. Bratko, Martin NG, Nichols RC, Wright MJ. Is there a genetic correlation between general factors of intelligence and personality? Twin Research and Human Genetics. 2015;18(03):234-242
DOI: 10.1017/thg.2015.28

Lubke GH, Ouwens KG, Moor MHM de, Trull TJ, Boomsma DI. Population heterogeneity of trait anger and differential associations of trait anger facets with borderline personality features, neuroticism, depression, Attention Deficit Hyperactivity Disorder (ADHD), and alcohol problems. Psychiatry Research. 2015;230(2):553-560
DOI: 10.1016/j.psychres.2015.10.003

Maier R, Moser G, Chen GB, Ripke S, Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Coryell W, Potash JB, Scheftner WA, Shi J, Weissman MM, Hultman CM, Landén M, Levinson DF, Kendler KS, Smoller JW, Wray NR, Lee SH, Boomsma DI, Geus EJC de, Hottenga JJ, Middeldorp CM, Willemsen G. Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder. The American Journal of Human Genetics. 2015;96(2):283-294, Open Access
DOI: 10.1016/j.ajhg.2014.12.006
Supplementary Materials (zip file)

Malik R, Freilinger T, Winsvold BS, Anttila V, Heiden J Vander, Traylor M, Vries B de, Holliday EG, Terwindt GM, Sturm J, Ligthart L, Van Duijn CM, Stefansson K, Worrall BB, Nyholt DR, Markus HS,  Maagdenberg AMJM van den, Cotsapas C, Zwart JA, Palotie A, The International Headache Genetics Consortium, Dichgans M, others for The METASTROKE Collaboration. Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants. Neurology. 2015;84(21):2132-2145
DOI: 10.1212/WNL.0000000000001606

Martin HC, Christ R, Hussin JG, O’Connell J, Gordon S, Mbarek H, Hottenga JJ, McAloney K, Willemsen G, Gasparini P, Pirastu N, Montgomery GW, Navarro P, Soranzo N, Toniolo D, Vitart V, Wilson JF, Marchini J, Boomsma DI, Martin NG, Donnelly P. Multicohort analysis of the maternal age effect on recombination. Nature Communications. 2015;6(7846):1-10, Open Access
DOI: 10.1038/ncomms8846
Supplementary Materials (zip file)

Mavioglu RN, Boomsma DI, Bartels M. Causes of individual differences in adolescent optimism: a study in Dutch twins and their siblings. European Child & Adolescent Psychiatry. 2015;24(11):1381-1388, Open Access
DOI: 10.1007/s00787-015-0680-x

Mbarek H, Milaneschi Y, Fedko IO, Hottenga JJ, Moor MHM de, Jansen R, Gelernter J, Sherva R, Willemsen G, Boomsma DI, Penninx BWJH, Vink JM. The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on AUDIT scores. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2015;168(8):739-748
DOI: 10.1002/ajmg.b.32379
Supplementary Materials (zip file)

Merjonen P, Dolan CV, Bartels M, Boomsma DI. Does breastfeeding behavior run in families? Evidence from twins, their sisters and their mothers in the Netherlands. Twin Research and Human Genetics. 2015;18(2):179-187
DOI: 10.1017/thg.2015.5

Mihailidis S, Bockmann M, McConnell E, Hughes T, Beijsterveldt CEM van, Boomsma DI, McMaster M, Townsend G. The influence of Chorion type on health measures at birth and dental development in Australian and Dutch twins: a comparative study. Twin Research and Human Genetics. 2015;18(4):368-374
DOI: 10.1017/thg.2015.43

Minica CC, Dolan CV, Kampert MMD, Boomsma DI, Vink JM. Sandwich corrected standard errors in family-based genome-wide association studies. European Journal of Human Genetics. 2015;23(3):388-394
DOI: 10.1038/ejhg.2014.94
Supplementary Materials (zip file)

Minica CC, Dolan CV, Hottenga JJ, Pool R, Fedko IO, Mbarek H, Huppertz C, Bartels M, Boomsma DI, Vink JM, The Genome of the Netherlands Consortium. Heritability, SNP- and Gene-Based Analyses of Cannabis Use Initiation and Age at Onset. Behavior Genetics. 2015;45(5):503-513, Open Access
DOI: 10.1007/s10519-015-9723-9
Supplementary Materials (zip file)

Molenaar D, Middeldorp CM, Beijsterveldt CEM van, Boomsma DI. Analysis of Behavioral and Emotional Problems in Children Highlights the Role of Genotype × Environment Interaction. Child Development. 2015;86(6):1999-2016
DOI: 10.1111/cdev.12451

Morris RW, Taylor AE, Fluharty ME, Bjørngaard JH, Åsvold BO, Elvestad Gabrielsen M, Campbell A, Marioni R, Kumari M, Korhonen T, Treur JL, Willemsen G, Vink JM, Boomsma DI, Preisig M, Borodulin K, Kaprio J, Kivimaki M, Smith BH, Hayward C, Romundstad PR, Sørensen TIA, Munafò MR, Sattar N, others. Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium. BMJ Open. 2015;5(8):e008808, Open Access
DOI: 10.1136/bmjopen-2015-008808
Supplementary Materials (zip file)

Neijts M, Lien R van, Kupper N, Boomsma DI, Willemsen G, Geus EJC de. Heritability and Temporal Stability of Ambulatory Autonomic Stress Reactivity in Unstructured 24-Hour Recordings. Psychosomatic Medicine. 2015;77(8):870-881
DOI: 10.1097/PSY.0000000000000227
Supplementary Materials (zip file)

The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium, O’Dushlaine C, Rossin L, Lee PH, Duncan L, Parikshak NN, Newhouse S, Neale BM, Ripke S, Purcell SM, Posthuma D, Boomsma DI, Geus EJC de, Hottenga JJ, Middeldorp CM, Penninx BWJH, Willemsen G, Craddock N, Kendler KS, Weiss LA, Wray NR, Zhao Z, Geschwind DH, Sullivan PF, Smoller JW, Holmans PA, Breen G, others. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nature Neuroscience. 2015;18(2):199-209
DOI: 10.1038/nn.3922
Supplementary Materials (zip file)

Nivard MG, Dolan CV, Kendler KS, Kan KJ, Willemsen G, Beijsterveldt CEM van, Lindauer RJL, Beek JHDA van, Geels LM, Bartels M, Middeldorp CM, Boomsma DI. Stability in symptoms of anxiety and depression as a function of genotype and environment: a longitudinal twin study from ages 3 to 63 years. Psychological Medicine. 2015;45(05):1039-1049
DOI: 10.1017/S003329171400213X
Supplementary Materials (zip file)

Nivard MG, Middeldorp CM, Dolan CV, Boomsma DI. Genetic and Environmental Stability of Neuroticism From Adolescence to Adulthood. Twin Research and Human Genetics. 2015;18(6):746-754
DOI: 10.1017/thg.2015.80

Nyholt DR, The International Headache Genetics Consortium, Anttila V, Winsvold BS, Kurth T, Stefansson H, Kallela M, Malik R, Vries B de, Terwindt GM, Ikram MA, Ligthart L, Boomsma DI, Strachan DP, Kubisch C, Ferrari MD, Maagdenberg AMJM van den, Dichgans M, Wessman M, Smith GD, Stefansson K, Chasman DI, Palotie A, others. Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies. Cephalalgia. 2015;35(6):489-499
DOI: 10.1177/0333102414547784
Supplementary Materials (zip file)

Oh G, Wang SC, Pal M, Chen ZF, Khare T, Tochigi M, Ng C, Yang YA, Kwan A, Kaminsky ZA, Mill J, Gunasinghe C, Tackett JL, Gottesman II, Willemsen G, Geus EJC de, Vink JM, Slagboom PE, Wray NR, Heath AC, Montgomery GW, TureckiG, Martin NG, Boomsma DI, McGuffin P, Kustra R, Petronis A. DNA Modification Study of Major Depressive Disorder: Beyond Locus-by-locus Comparisons. Biological Psychiatry. 2015;77(3):246-255, Open Access
DOI: 10.1016/j.biopsych.2014.06.016
Supplementary Materials (zip file)

Pappa I, Fedko IO, Mileva-Seitz VR, Hottenga JJ, Bakermans-Kranenburg MJ, Bartels M, Beijsterveldt CEM van, Jaddoe VWV, Middeldorp CM, Rippe RCA, Rivadeneira F, Tiemeier H, Verhulst FC, IJzendoorn MH van, Boomsma DI. Single Nucleotide Polymorphism Heritability of Behavior Problems in Childhood: Genome-Wide Complex Trait Analysis. Journal of the American Academy of Child & Adolescent Psychiatry. 2015;54(9):737-744
DOI: 10.1016/j.jaac.2015.06.004
Supplementary Materials (zip file)

Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Groen-Blokhuis MM, Australian Asthma Genetics Consortium (AAGC), Hottenga JJ, Middeldorp CM, Boomsma DI, Lau S, Hübner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, Weidinger S, EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, many others. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature Genetics. 2015;47(12):1449-1456
DOI: 10.1038/ng.3424
Supplementary Materials (zip file)

Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, Geus EJC de, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S, Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J, Social Science Genetic Association Consortium, Willemsen G, Zhu Z, Boomsma DI, Wray NR, Penninx BWJH. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Molecular Psychiatry. 2015;20(6):735-743
DOI: 10.1038/mp.2015.50
Supplementary Materials (zip file)

Power RA, Steinberg S, Bjornsdottir G, Rietveld CA, Abdellaoui A, Nivard MG, Johannesson M, Galesloot TE, Hottenga JJ, Willemsen G, Cesarini D, Benjamin DJ, Magnusson PKE, Ullén F, Tiemeier H, Hofman A, Rooij FJA van, Bragi Walters G, Sigurdsson E, Thorgeirsson TE, Ingason A, Helgason A, Kong A, Kiemeney LA, Koellinger P, Boomsma DI, Gudbjartsson D, Stefansson H, Stefansson K. Polygenic risk scores for schizophrenia and bipolar disorder predict creativity. Nature Neuroscience. 2015;18(7):953-955
DOI: 10.1038/nn.4040
Supplementary Materials (zip file)

Rahmioglu N, Macgregor S, Drong AW, Hedman AK, Harris HR, Randall JC, Prokopenko I, The International EndoGene Consortium, The GIANT Consortium, Hottenga JJ, Boomsma DI, Nyholt DR, Morris AP, Montgomery GW, Missmer SA, Lindgren CM, Zondervan KT, others. Genome-wide Enrichment Analysis between Endometriosis and Obesity-related Traits Reveals Novel Susceptibility Loci. Human Molecular Genetics. 2015;24(4):1185-1199, Open Access
DOI: 10.1093/hmg/ddu516
Supplementary Materials (zip file)

Robinson MR, Hemani G, Medina-Gomez C, Mezzavilla M, Esko T, Shakhbazov K, Powell JE, Vinkhuyzen AAE, Berndt SI, Boomsma DI, Geus EJC de, Hottenga JJ, Ingelsson E, Loos RJF, Magnusson PKE, Martin NG, Montgomery GW, North KE, Pedersen NL, Spector TD, Speliotes EK, Goddard ME, Yang J, Visscher PM, others. Population genetic differentiation of height and body mass index across Europe. Nature Genetics. 2015;47(11):1357-1362
DOI: 10.1038/ng.3401
Supplementary Materials (zip file)

Schnack HG, Haren NEM van, Brouwer RM, Evans A, Durston S, Boomsma DI, Kahn RS, Hulshoff Pol HE. Changes in Thickness and Surface Area of the Human Cortex and Their Relationship with Intelligence. Cerebral Cortex. 2015;25(6):1608-1617, Open Access
DOI: 10.1093/cercor/bht357
Supplementary Materials (zip file)

Shah S, Bonder MJ, Marioni RE, Zhu Z, McRae AF, Zhernakova A, Harris SE, Liewald D, Henders AK, Mendelson MM, Liu C, Joehanes R, Liang L, BIOS Consortium, Boomsma DI, Pool R, Dongen J van, Hottenga JJ, Levy D, Martin NG, Starr JM, Wijmenga C, Wray NR, Yang J, Montgomery GW, Franke L, Deary IJ, Visscher PM. Improving Phenotypic Prediction by Combining Genetic and Epigenetic Associations. The American Journal of Human Genetics. 2015;97(1):75-85, Open Access
DOI: 10.1016/j.ajhg.2015.05.014
Supplementary Materials (zip file)

Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Helmer Q, Geus EJC de, Penninx BWJH, Oostra BA, Slagboom PE, Snieder H, Uitterlinden AG, Van Duijn CM, Visscher PM, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJF, Cupples LA, Morris AP, Lindgren CM, Mohlke KL, many others. New genetic loci link adipose and insulin biology to body fat distribution. Nature. 2015;518(7538):187-196
DOI: 10.1038/nature14132
Supplementary Materials (zip file)

Silventoinen K, Jelenkovic A, Sund R, Honda C, Aaltonen S, Yokoyama Y, Tarnoki AD, Tarnoki DL, Ning F, Ji F, Bartels M, Beijsterveldt CEM van, Rasmussen F, Sung J, Harris JR, Willemsen G, Busjahn A, Goldberg JH, Boomsma DI, Hur YM, Sorensen TIA, Kaprio J, many others. The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits. Twin Research and Human Genetics. 2015;18(4):348-360
DOI: 10.1017/thg.2015.29
Supplementary Materials (zip file)

Sirota M, Willemsen G, Sundar P, Pitts SJ, Potluri S, Prifti E, Kennedy S, Ehrlich SD, Neuteboom J, Kluft C, Malone KE, Cox DR, Geus EJC de, Boomsma DI. Effect of Genome and Environment on Metabolic and Inflammatory Profiles. PLOS ONE. 2015; 10(4):e0120898, Open Access
DOI: 10.1371/journal.pone.0120898
Supplementary Materials (zip file)

Stoffers D, Diaz BA, Chen G, den Braber A, van ‘t Ent D, Boomsma DI, Mansvelder HD, Geus EJC de, Someren EJW van, Linkenkaer-Hansen K. Resting-State fMRI Functional Connectivity Is Associated with Sleepiness, Imagery, and Discontinuity of Mind. PLOS ONE. 2015;10(11):e0142014, Open Access
DOI: 10.1371/journal.pone.0142014

Strohmaier J, Dongen J van, Willemsen G, Nyholt DR, Zhu G, Codd V, Novakovic B, Hansell N, Wright MJ, Rietschel L, Streit F, Henders AK, Montgomery GW, Samani NJ, Gillespie NA, Hickie IB, Craig JM, Saffery R, Boomsma DI, Rietschel M, Martin NG. Low Birth Weight in MZ Twins Discordant for Birth Weight is Associated with Shorter Telomere Length and lower IQ, but not Anxiety/Depression in Later Life. Twin Research and Human Genetics. 2015;18(2):198-209
DOI: 10.1017/thg.2015.3

Surakka I, Horikoshi M, Mägi R, Sarin AP, Mahajan A, Lagou V, Marullo L, Ferreira T, Miraglio B, Timonen S, Hottenga JJ, Geus EJC de, Penninx BWJH, Willemsen G, Slagboom PE, Van Duijn CM, Boomsma DI, Ikonen E, Kallioniemi O, Pietiäinen V, Lindgren CM, Stefansson K, Palotie A, McCarthy MI, Morris AP, Prokopenko I, Ripatti S, many others for the ENGAGE Consortium. The impact of low-frequency and rare variants on lipid levels. Nature Genetics. 2015;47(6):589-597
DOI: 10.1038/ng.3300
Supplementary Materials (zip file)

Swagerman SC, Geus EJC de, Koenis MMG, Hulshoff Pol HE, Boomsma DI, Kan KJ. Domain dependent associations between cognitive functioning and regular voluntary exercise behavior. Brain and Cognition. 2015;97:32-39
DOI: 10.1016/j.bandc.2015.04.001

Toulopoulou T, Haren N van, Zhang X, Sham PC, Cherny SS, Campbell DD, Picchioni M, Murray R, Boomsma DI, Hulshoff Pol HE, Brouwer R, Schnack H, Fañanás L, Sauer H, Nenadic I, Weisbrod M, Cannon TD, Kahn RS. Reciprocal causation models of cognitive vs volumetric cerebral intermediate phenotypes for schizophrenia in a pan-European twin cohort. Molecular Psychiatry. 2015;20(11):1386-1396
DOI: 10.1038/mp.2014.152
Supplementary Materials (zip file)

Treur JL, Vink JM, Boomsma DI, Middeldorp CM. Spousal resemblance for smoking: Underlying mechanisms and effects of cohort and age. Drug and Alcohol Dependence. 2015;153:221-228
DOI: 10.1016/j.drugalcdep.2015.05.018
Supplementary Materials (zip file)

Treur JL, Willemsen G, Bartels M, Geels LM, Beek JHDA van, Huppertz C, Beijsterveldt CEM van, Boomsma DI, Vink JM. Smoking during adolescence as a risk factor for attention problems. Biological Psychiatry. 2015;78(9):656-663
DOI: 10.1016/j.biopsych.2014.06.019
Supplementary Materials (zip file)

Tsai PC, Dongen J van, Tan Q, Willemsen G, Christiansen L, Boomsma DI, Spector TD, Valdes AM, Bell JT. DNA Methylation Changes in the IGF1R Gene in Birth Weight Discordant Adult Monozygotic Twins. Twin Research and Human Genetics. 2015;18(06):635-646
DOI: 10.1017/thg.2015.76

Vaez A, Jansen R, Prins BP, Hottenga JJ, Geus EJC de, Boomsma DI, Penninx BWJH, Nolte IM, Snieder H, Alizadeh BZ. An in silico Post-GWAS Analysis of C-Reactive Protein Loci Suggests an Important Role for Interferons. Circulation: Cardiovascular Genetics. 2015;8(3):487-497, Open Access
DOI: 10.1161/CIRCGENETICS.114.000714
Supplementary Material (zip file)

Valk RJP van der, Kreiner-Møller E, Kooijman MN, Guxens M, Stergiakouli E, Sääf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Early Genetics & Lifecourse Epidemiology (EAGLE) Consortium, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Boomsma DI, Groen-Blokhuis MM, Pennell CE, Niinikoski H, Dedoussis GV, McCarthy MI, Frayling TM, Sunyer J, Timpson NJ, Rivadeneira F, Bonnelykke K, Jaddoe VWV, many others for the Early Growth Genetics (EGG) Consortium. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Human Molecular Genetics. 2015;24(4):1155-1168, Open Access
DOI: 10.1093/hmg/ddu510
Supplementary Materials (zip file)

Visscher CM, Ligthart L, A.A. Schuller, F. Lobbezoo, Jongh A de, CM.H.H. van Houtem, Boomsma DI. Comorbid Disorders and Sociodemographic Variables in Temporomandibular Pain in the General Dutch Population. Journal of Oral & Facial Pain and Headache. 2015;29(1):51-59
DOI: 10.11607/ofph.1324

Willemsen G, Ward KJ, Bell CG, Christensen K, Bowden J, Dalgård C, Harris JR, Kaprio J, Lyle R, Magnusson PKE, Mather KA, Ordonana JR, Perez-Riquelme F, Pedersen NL, Pietiläinen KH, Sachdev PS, Boomsma DI, Spector T. The Concordance and Heritability of Type 2 Diabetes in 34,166 Twin Pairs From International Twin Registers: The Discordant Twin (DISCOTWIN) Consortium. Twin Research and Human Genetics. 2015;18(6):762-771
DOI: 10.1017/thg.2015.83

Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO, Hottenga JJ, Geus EJC de, Slagboom PE, Willemsen G, Boomsma DI, CHARGE Consortium, DIAGRAM Consortium, GLGC Consortium, Global-BPGen Consortium, ICBP Consortium, MAGIC Consortium, Strachan DP, Stefansson K, Van Duijn CM, Hirschhorn JN, Lindgren CM, Heid IM, North KE, Borecki IB, Kutalik Z, Loos RJF, many others. The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. PLOS GENETICS. 2015;11(10):e1005378, Open Access
DOI: 10.1371/journal.pgen.1005378
Supplementary Materials (zip file)

Winsvold BS, Nelson CP, Malik R, Gormley P, Anttila V, Heiden J Vander, Elliott KS, Jacobsen LM, Palta P, Amin N, Ligthart L, Boomsma DI, Van Duijn CM, Wessman M, Kurth T, Kubisch C, Dichgans M, Chasman DI, Cotsapas C, Zwart JA, Samani NJ, Palotie A, others. Genetic analysis for a shared biological basis between migraine and coronary artery disease. Neurology Genetics. 2015;1(1):e10, Open Access
DOI: 10.1212/NXG.0000000000000010
Supplementary Materials (zip file)

Xu T, Brandmaier S, Messias AC, Herder C, Draisma HHM, Demirkan A, Yu Z, Ried JS, Haller T, Heier M, Willemsen G, Pool R, Suhre K, Adamski J, Illig T, Rathmann W, Roden M, Peters A, Van Duijn CM, Boomsma DI, Meitinger T, Wang-Sattler R, others. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes. Diabetes Care. 2015;38(10):1858-1867
DOI: 10.2337/dc15-0658
Supplementary Materials (zip file)

Zeeuw EL de, Beijsterveldt CEM van, Lubke GH, Glasner TJ, Boomsma DI. Childhood ODD and ADHD Behavior: The Effect of Classroom Sharing, Gender, Teacher Gender and Their Interactions. Behavior Genetics. 2015;45(4):394-408, Open Access
DOI: 10.1007/s10519-015-9712-z
Supplementary Materials (zip file)

Zeeuw EL de, Geus EJC de, Boomsma DI. Meta-analysis of twin studies highlights the importance of genetic variation in primary school educational achievement. Trends in Neuroscience and Education. 2015;4(3):69-76
DOI: 10.1016/j.tine.2015.06.001
Supplementary Materials (zip file)

Zilhão NR, Smit DJA, den Braber A, Dolan CV, Willemsen G, Boomsma DI, Cath DC. Genetic and Environmental Contributions to Stability in Adult Obsessive Compulsive Behavior. Twin Research and Human Genetics. 2015;18(01):52-60
DOI: 10.1017/thg.2014.77
Supplementary Materials (zip file)

Zilhão NR, Padmanabhuni SS, Pagliaroli L, Barta C, BIOS Consortium, Smit DJA, Cath DC, Nivard MG, Baselmans BML, Dongen J van, Paschou P, Boomsma DI. Epigenome-Wide Association Study of Tic Disorders. Twin Research and Human Genetics. 2015;18(06):699-709
DOI: 10.1017/thg.2015.72
Supplementary Materials (zip file)

N. Zwaveling-Soonawala, Beijsterveldt CEM van, Mesfum ET, Wiedijk B, Oomen P, Finken MJJ, Boomsma DI, Trotsenburg ASP van. Fetal environment is a major determinant of the neonatal blood thyroxine level: results of a large Dutch twin-study. The Journal of Clinical Endocrinology & Metabolism. 2015;100(6):2388-2395, Open Access
DOI: 10.1210/jc.2015-1429