Publications in scientific journals: 2013

Research based on NTR data

2013

Abdellaoui A, Hottenga JJ, Knijff P de, Nivard MG, Xiao X, Scheet P, Brooks A, Ehli EA, Hu Y, Davies GE, Hudziak JJ, Sullivan PF, Beijsterveldt CEM van, Willemsen G, Geus EJC de, Penninx BWJH, Boomsma DI. Population structure, migration, and diversifying selection in the Netherlands. European Journal of Human Genetics. 2013;21(11):1277-1285
DOI: 10.1038/ejhg.2013.48
Supplementary Materials (zip file)

Abdellaoui A, Hottenga JJ, Xiao X, Scheet P, Ehli EA, Davies GE, Hudziak JJ, Smit DJA, Bartels M, Willemsen G, Brooks A, Sullivan PF, Smit JH, Geus EJC de, Penninx BWJH, Boomsma DI. Association Between Autozygosity and Major Depression: Stratification Due to Religious Assortment. Behavior Genetics. 2013;43(6):455-467
DOI: 10.1007/s10519-013-9610-1

Amin N, Hottenga JJ, Hansell NK, Janssens ACJW, Moor MHM de, Madden PAF, Zorkoltseva IV, Penninx BWJH, Terracciano A, Uda M, Willemsen G, Pergadia ML, Medland SE, Axenovich TI, Geus EJC de, Montgomery GW, Wright MJ, Oostra BA, Martin NG, Boomsma DI, Duijn CM van, others. Refining genome-wide linkage intervals using a meta-analysis of genome-wide association studies identifies loci influencing personality dimensions. European Journal of Human Genetics. 2013;21(8):876-882
DOI: 10.1038/ejhg.2012.263
Supplementary Materials (zip file)

Anttila V, Winsvold BS, Gormley P, Kurth T, Bettella F, McMahon G, Kallela M, Malik R, Vries B de, Terwindt G, Ligthart L, Hottenga JJ, Vink JM, North American Brain Expression Consortium, UK Brain Expression Consortium, Penninx BWJH, Boomsma DI, Duijn CM van, Ferrari MD, Maagdenberg AMJM van den, Dichgans M, Wessman M, Davey Smith G, Stefansson K, Daly MJ, Nyholt DR, Chasman DI, Palotie A, many others for The International Headache Genetics Consortium. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nature Genetics. 2013;45(8):912-917
DOI: 10.1038/ng.2676
Supplementary Materials (zip file)

Bartels M, Cacioppo JT, Beijsterveldt CEM van, Boomsma DI. Exploring the Association Between Well-Being and Psychopathology in Adolescents. Behavior Genetics. 2013;43(3):177-190, Open Access
DOI: 10.1007/s10519-013-9589-7

Beek JHDA van, Moor MHM de, Geus EJC de, Lubke GH, Vink JM, Willemsen G, Boomsma DI. The Genetic Architecture of Liver Enzyme Levels: GGT, ALT and AST. Behavior Genetics. 2013;43(4):329-339
DOI: 10.1007/s10519-013-9593-y
Supplementary Materials (zip file)

Beijsterveldt CEM van, Groen-Blokhuis M, Hottenga JJ, Franic S, Hudziak JJ, Lamb D, Huppertz C, Zeeuw E de, Nivard M, Schutte N, Swagerman S, Brouwer C, Stroet T, Ehli EA, Davies GE, Scheet P, Orlebeke JF, Kan K-J, Smit DJA, Dolan CV, Middeldorp CM, Geus EJC de, Bartels M, Boomsma DI, others. The Young Netherlands Twin Register (YNTR): Longitudinal Twin and Family Studies in Over 70,000 Children. Twin Research and Human Genetics. 2013;16(1):252-267
DOI: 10.1017/thg.2012.118

Berkelaar M, Eekhoff EMW, Simonis-Bik AMC, Boomsma DI, Diamant M, IJzerman RG, Dekker JM, Hart LM ’t, Geus EJC de. Effects of induced hyperinsulinaemia with and without hyperglycaemia on measures of cardiac vagal control. Diabetologia. 2013;56(6):1436-1443
DOI: 10.1007/s00125-013-2848-6

Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Hottenga JJ, Willemsen G, Boomsma DI, Penninx BWJH, McCarthy MI, Speliotes EK, North KE, Loos RJF, Ingelsson E, others. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nature Genetics. 2013;45(5):501-512
DOI: 10.1038/ng.2606
Supplementary Materials (zip file)

Boersma M, Smit DJA, Boomsma DI, Geus EJC de, Delemarre - van de Waal HA, Stam CJ. Growing trees in child brains: Graph theoretical analysis of EEG derived minimum spanning tree in 5 and 7 year old children reflects brain maturation. Brain Connectivity. 2013;3(1):50-60
DOI: 10.1089/brain.2012.0106
Supplementary Materials (zip file)

Boomsma DI. Twin, association and current “omics” studies. Journal of Maternal-Fetal and Neonatal Medicine. 2013;26(S2):9-12
DOI: 10.3109/14767058.2013.830405

Boomsma DI. Book Review: Far from the Tree by Andrew Solomon. Twin Research and Human Genetics. 2013;16(4):922
DOI: 10.1017/thg.2013.37

Bot M, Vink JM, Willemsen G, Smit JH, Neuteboom J, Kluft C, Boomsma DI, Penninx BWJH. Exposure to secondhand smoke and depression and anxiety: A report from two studies in the Netherlands. Journal of Psychosomatic Research. 2013;75(5):431-436
DOI: 10.1016/j.jpsychores.2013.08.016

Braber A den, Geus EJC de, Boomsma DI, Ent D van 't. Obsessive–Compulsive Symptoms and Related Sex Differences in Brain Structure: An MRI Study in Dutch Twins. Twin Research and Human Genetics. 2013;16(2):516-524
DOI: 10.1017/thg.2013.10

Braber A den, Bohlken MM, Brouwer RM, Ent D van 't, Kanai R, Kahn RS, Geus EJC de, Hulshoff Pol HE, Boomsma DI. Heritability of subcortical brain measures: A perspective for future genome-wide association studies. NeuroImage. 2013;83:98-102
DOI: 10.1016/j.neuroimage.2013.06.027

Braber A den, Ent D van 't, Stoffers D, Linkenkaer-Hansen K, Boomsma DI, Geus EJC de. Sex differences in gray and white matter structure in age-matched unrelated males and females and opposite-sex siblings. International Journal of Psychological Research. 2013;6(Special Issue: Social Neuroscience):7-21

Brandys MK, Kas MJH, Elburg AA van, Ophoff R, Slof - Op't Landt MCT, Middeldorp CM, Boomsma DI, Furth EF van, Slagboom PE, Adan RAH. The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis. The World Journal of Biological Psychiatry. 2013;14(6):441-451
DOI: 10.3109/15622975.2011.605470
Supplementary Materials (zip file)

Brant AM, Munakata Y, Boomsma DI, Defries JC, Haworth CMA, Keller MC, Martin NG, McGue M, Petrill SA, Plomin R, Wadsworth SJ, Wright MJ, Hewitt JK. The Nature and Nurture of High IQ: An Extended Sensitive Period for Intellectual Development. Psychological Science. 2013;24(8):1487-1495
DOI: 10.1177/0956797612473119
Supplementary Materials (zip file)

Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G, Albrecht E, Amin N, Beekman M, Geus EJC de, Vink JM, Spector TD, Slagboom PE, Martin NG, Samani NJ, Duijn CM van, Boomsma DI, others. Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. European Journal of Human Genetics. 2013;21(10):1163-1168
DOI: 10.1038/ejhg.2012.303
Supplementary Materials (zip file)

Carpenter RW, Tomko RL, Trull TJ, Boomsma DI. Gene-Environment Studies and Borderline Personality Disorder: A Review. Current Psychiatry Reports. 2013;15(1):336
DOI: 10.1007/s11920-012-0336-1

Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Suchiman HED, Willemsen G, CARDIoGRAM consortium, Hovatta I, Gieger C, Metspalu A, Boomsma DI, Järvelin MR, Slagboom PE, Thompson JR, Spector TD, Harst P van der, Samani NJ, many others. Identification of seven loci affecting mean telomere length and their association with disease. Nature Genetics. 2013;45(4):422-427
DOI: 10.1038/ng.2528
Supplementary Materials (zip file)

Cousminer DL, Berry DJ, Timpson NJ, Ang W, Thiering E, Groen-Blokhuis MM, Bartels M, Boomsma DI, Järvelin MR, McCarthy MI, Ripatti S, Widen E, Early Growth Genetics (EGG) Consortium, others. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics. 2013;22(13):2735-2747, Open Access
DOI: 10.1093/hmg/ddt104
Supplementary Materials (zip file)

Cross-Disorder Group of the Psychiatric Genomics Consortium, Smoller JW, Craddock N, Kendler K, Lee PH, Neale BM, Boomsma DI, Geus EJC de, Hottenga JJ, Middeldorp CM, others. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. The Lancet. 2013;381(9875):1371-1379, Open Access
DOI: 10.1016/S0140-6736(12)62129-1
Supplementary Materials (zip file)

Cross-Disorder Group of the Psychiatric Genomics Consortium, Hong Lee S, Ripke S, Neale BM, Faraone SV, Purcell SM, Boomsma DI, Geus EJC de, Hottenga JJ, Middeldorp CM, Montgomery GW, Neale MC, Penninx BWJH, Posthuma D, Willemsen G, Craddock N, Sullivan PF, Smoller JW, Kendler KS, Wray NR, others. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 2013;45(9):984-994
DOI: 10.1038/ng.2711
Supplementary Materials (zip file)

Culverhouse RC, Bowes L, Breslau N, Nurnberger Jr JI, Burmeister M, Fergusson DM, Munafò M, Saccone NL, Bierut LJ, the 5-HTTLPR, Stress, and Depression Consortium. Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression. BMC Psychiatry. 2013;13(304), Open Access
DOI: 10.1186/1471-244X-13-304
Supplementary Materials (zip file)

Diaz BA, Sluis S van der, Moens S, Benjamins JS, Migliorati F, Stoffers D, Braber A den, Poil S-S, Hardstone R, Ent D van ’t, Boomsma DI, Geus EJC de, Mansvelder HD, Someren EJW van, Linkenkaer-Hansen K. The Amsterdam Resting-State Questionnaire reveals multiple phenotypes of resting-state cognition. Frontiers in Human Neuroscience. 2013;7:446, Open Access
DOI: 10.3389/fnhum.2013.00446

Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S, Ganna A, Chen J, Willemsen G, Boomsma DI, Deloukas P, Mohlke KL, Ingelsson E, Abecasis GR, Daly MJ, Neale BM, Kathiresan S, others. Common variants associated with plasma triglycerides and risk for coronary artery disease. Nature Genetics. 2013;45(11):1345-1352
DOI: 10.1038/ng.2795
Supplementary Materials (zip file)

Dongen J van, Boomsma DI. The evolutionary paradox and the missing heritability of schizophrenia. American Journal of Medical Genetics Part B. Neuropsychiatric Genetics. 2013;162(2):122-136
DOI: 10.1002/ajmg.b.32135

Dongen J van, Willemsen G, Chen W-M, Geus EJC de, Boomsma DI. Heritability of metabolic syndrome traits in a large population-based sample. Journal of Lipid Research. 2013;54(10):2914-2923, Open Access
DOI: 10.1194/jlr.P041673
Supplementary Materials (zip file)

Draisma HHM, Reijmers TH, Meulman JJ, Greef J van der, Hankemeier T, Boomsma DI. Hierarchical clustering analysis of blood plasma lipidomics profiles from mono- and dizygotic twin families. European Journal of Human Genetics. 2013;21(1):95-101
DOI: 10.1038/ejhg.2012.110
Supplementary Materials (zip file)

Draisma HHM, Beekman M, Pool R, Ommen GJB van, Vaarhorst AAM, Craen AJM de, Willemsen G, Slagboom PE, Boomsma DI. Familial Resemblance for Serum Metabolite Concentrations. Twin Research and Human Genetics. 2013;16(05):948-961
DOI: 10.1017/thg.2013.59
Supplementary Materials (zip file)

Fall T, Hägg S, Mägi R, Ploner A, Fischer K, Horikoshi M, Sarin A-P, Thorleifsson G, Ladenvall C, Kals M, Draisma HHM, Hottenga JJ, Willemsen G, Penninx BWJH, Boomsma DI, Geus EJC de, Vartiainen E, Hofman A, Ripatti S, Metspalu A, Thorsteinsdottir U, Stefansson K, Pedersen NL, McCarthy MI, Ingelsson E, Prokopenko I, others for the European Network for Genetic and Genomic Epidemiology (ENGAGE) consortium. The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis. PLOS Medicine. 2013;10(6):e1001474, Open Access
DOI: 10.1371/journal.pmed.1001474
Supplementary Materials (zip file)

Fernández-Rhodes L, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, Hottenga JJ, Willemsen G, Boomsma DI, Rose LM, Ridker PM, Poole C, Hirschhorn JN, Murabito JM, Chasman DI, Widen E, North KE, Ong KK, Franceschini N, many others. Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent. American Journal of Epidemiology. 2013;178(3):451-460, Open Access
DOI: 10.1093/aje/kws473
Supplementary Materials (zip file)

Franic S, Dolan CV, Borsboom D, Hudziak JJ, Beijsterveldt CEM van, Boomsma DI. Can Genetics Help Psychometrics? Improving Dimensionality Assessment Through Genetic Factor Modeling. Psychological Methods. 2013;18(3):406-433
DOI: 10.1037/a0032755

Geels LM, Vink JM, Beek JHDA van, Bartels M, Willemsen G, Boomsma DI. Increases in alcohol consumption in women and elderly groups: evidence from an epidemiological study. BMC Public Health. 2013;13(207), Open Access
DOI: 10.1186/1471-2458-13-207
Supplementary Materials (zip file)

Geels LM, Vink JM, Beijsterveldt CEM van, Bartels M, Boomsma DI. Developmental Prediction Model for Early Alcohol Initiation in Dutch Adolescents. Journal of Studies on Alcohol and Drugs. 2013;74(1):59-70
DOI: 10.15288/jsad.2013.74.59

Global Lipids Genetics Consortium, Willer CJ, Willemsen G, Boomsma DI, many others. Discovery and refinement of loci associated with lipid levels. Nature Genetics. 2013;45(11):1274-1283
DOI: 10.1038/ng.2797
Supplementary Materials (zip file)

Groen-Blokhuis MM, Franic S, Beijsterveldt CEM van, Geus EJC de, Bartels M, Davies GE, Ehli EA, Xiao X, Scheet PA, Althoff R, Hudziak JJ, Middeldorp CM, Boomsma DI. A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2013;162(5):457-465, Open Access
DOI: 10.1002/ajmg.b.32175
Supplementary Materials (zip file)

Hart LM ‘t, Fritsche A, Nijpels G, Leeuwen N van, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, Helmer Q, Willemsen G, Koning EJP de, Häring H-U, Pedersen O, Groop L, Geus EJC de, Slagboom PE, Boomsma DI, Eekhoff EMW, Pearson ER, Diamant M, others. The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. Diabetes. 2013;62(9):3275-3281, Open Access
DOI: 10.2337/db13-0227
Supplementary Materials (zip file)

Florez JC. Commentary on 't Hart 62(9):3275-3281 : Pharmacogenetic Perturbations in Humans as a Tool to Generate Mechanistic Insight. Diabetes, 62(9):3019-3021

Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Boomsma DI, Geus EJC de, Penninx BWJH, Räikkönen K, Tanaka T, Duijn CM van, Grabe HJ, Launer LJ, Lunetta KL, Mosley Jr TH, Newman AB, Tiemeier H, Murabito J, many others. A Genome-Wide Association Study of Depressive Symptoms. Biological Psychiatry. 2013;73(7):667-678
DOI: 10.1016/j.biopsych.2012.09.033
Supplementary Materials (zip file)

Hemani G, Yang J, Vinkhuyzen A, Powell JE, Willemsen G, Hottenga JJ, Abdellaoui A, Mangino M, Valdes AM, Medland SE, Madden PA, Heath AC, Henders AK, Nyholt DR, Geus EJC de, Magnusson PKE, Ingelsson E, Montgomery GW, Spector TD, Boomsma DI, Pedersen NL, Martin NG, Visscher PM. Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs. American Journal of Human Genetics. 2013;93(5):865-875, Open Access
DOI: 10.1016/j.ajhg.2013.10.005
Supplementary Materials (zip file)

Heuvel MP van den, Soelen ILC van, Stam CJ, Kahn RS, Boomsma DI, Hulshoff Pol HE. Genetic control of functional brain network efficiency in children. European Neuropsychopharmacology. 2013;23(1):19-23, Open Access
DOI: 10.1016/j.euroneuro.2012.06.007

Hoed M den, Eijgelsheim M, Esko T, Brundel BJJM, Peal DS, Draisma HHM, Geus EJC de, Hottenga JJ, Willemsen G, Boomsma DI, Sibon OCM, Milan DJ, Snieder H, Samani NJ, Loos RJF, others. Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders. Nature Genetics. 2013;45(6):621-631
DOI: 10.1038/ng.2610
Supplementary Materials (zip file)

Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B, Evans DM, Charoen P, Hottenga JJ, Geus EJC de, Vink JM, Willemsen G, Boomsma DI, Lawlor DA, Smith GD, Frayling TM, McCarthy MI, Grant SFA, Jaddoe VWV, Jarvelin M-R, Timpson NJ, Prokopenko I, Freathy RM, many others. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nature Genetics. 2013;45(1):76-82
DOI: 10.1038/ng.2477

Houtem CMHH van, Laine ML, Boomsma DI, Ligthart L, Wijk AJ van, Jongh A de. A review and meta-analysis of the heritability of specific phobia subtypes and corresponding fears. Journal of Anxiety Disorders. 2013;27(4):379-388
DOI: 10.1016/j.janxdis.2013.04.007

Hu YJ, Berndt SI, Gustafsson S, Ganna A, Genetic Investigation of ANthropometric Traits (GIANT) Consortium, Hottenga JJ, Willemsen G, Boomsma DI, Hirschhorn J, North KE, Ingelsson E, Lin DY. Meta-analysis of Gene-Level Associations for Rare Variants Based on Single-Variant Statistics. American Journal of Human Genetics. 2013;93(2):236-248, Open Access
DOI: 10.1016/j.ajhg.2013.06.011
Supplementary Materials (zip file)

Kan KJ, Dolan CV, Nivard MG, Middeldorp CM, Beijsterveldt CEM van, Willemsen G, Boomsma DI. Genetic and Environmental Stability in Attention Problems Across the Lifespan: Evidence From the Netherlands Twin Register. Journal of the American Academy of Child & Adolescent Psychiatry. 2013;52(1):12-25
DOI: 10.1016/j.jaac.2012.10.009

Kan KJ, Wicherts JM, Dolan CV, Maas HLJ van der. On the Nature and Nurture of Intelligence and Specific Cognitive Abilities: The More Heritable, the More Culture Dependent. Psychological Science. 2013;24(12):2420-2428
DOI: 10.1177/0956797613493292
Supplementary Materials (zip file)

Kiezun A, Pulit SL, Francioli LC, Dijk F van, Swertz M, Boomsma DI, Duijn CM van, Slagboom PE, Ommen GJB van, Wijmenga C, Genome of the Netherlands Consortium, Bakker PIW de, Sunyaev SR. Deleterious Alleles in the Human Genome Are on Average Younger Than Neutral Alleles of the Same Frequency. PLOS Genetics. 2013;9(2):e1003301, Open Access
DOI: 10.1371/journal.pgen.1003301

Koenis MMG, Brouwer RM, Baal GCM van, Soelen ILC van, Peper JS, Leeuwen M van, Delemarre-van de Waal HA, Boomsma DI, Hulshoff Pol HE. Longitudinal Study of Hormonal and Physical Development in Young Twins. The Journal of Clinical Endocrinology & Metabolism. 2013;98(3):518-527, Open Access
DOI: 10.1210/jc.2012-3361
Supplementary Materials (zip file)

Kuny AV, Althoff RR, Copeland W, Bartels M, Beijsterveldt CEM van, Baer J, Hudziak JJ. Separating the Domains of Oppositional Behavior: Comparing Latent Models of the Conners’ Oppositional Subscale. Journal of the American Academy of Child & Adolescent Psychiatry. 2013;52(2):172-183
DOI: 10.1016/j.jaac.2012.10.005

Ligthart L, Gerrits MMJG, Boomsma DI, Penninx BWJH. Anxiety and Depression Are Associated With Migraine and Pain in General: An Investigation of the Interrelationships. The Journal of Pain. 2013;14(4):363-370
DOI: 10.1016/j.jpain.2012.12.006

Loos MJHM van der, Rietveld CA, Eklund N, Koellinger PD, Rivadeneira F, Abecasis GR, Ankra-Badu GA, Baumeister SE, Benjamin DJ, Biffar R, Boomsma DI, Geus EJC de, Hottenga JJ, Völzke H, Wichmann HE, Wild PS, Willems SM, Willemsen G, Rooij FJA van, Groenen PJF, Uitterlinden AG, Hofman A, Thurik AR, others. The Molecular Genetic Architecture of Self-Employment. PLOS One. 2013;8(4):e60542, Open Access
DOI: 10.1371/journal.pone.0060542
Supplementary Materials (zip file)

Lubke GH, Laurin C, Walters R, Eriksson N, Hysi P, Spector TD, Montgomery GW, Martin NG, Medland SE, Boomsma DI. Gradient Boosting as a SNP Filter: an Evaluation Using Simulated and Hair Morphology Data. Journal of Datamining in Genomics & Proteomics. 2013;4(4), Open Access
DOI: 10.4172/2153-0602.1000143

Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Boomsma DI, Penninx BWJH, Geus EJC de, Hottenga JJ, Middeldorp CM, Willemsen G, Zitman FG, Neale BM, Daly M, Levinson DF, Sullivan PF, many others. A mega-analysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry. 2013;18(4):497-511
DOI: 10.1038/mp.2012.21
Supplementary Materials (zip file)

Minica CC, Dolan CV, Hottenga JJ, Willemsen G, Vink JM, Boomsma DI. The Use of Imputed Sibling Genotypes in Sibship-Based Association Analysis: On Modeling Alternatives, Power and Model Misspecification. Behavior Genetics. 2013;43(3):254-266
DOI: 10.1007/s10519-013-9590-1

Molenaar D, Sluis S van der, Boomsma DI, Haworth CMA, Hewitt JK, Martin NG, Plomin R, Wright MJ, Dolan CV. Genotype by Environment Interactions in Cognitive Ability: A Survey of 14 Studies from Four Countries Covering Four Age Groups. Behavior Genetics. 2013;43(3):208-219
DOI: 10.1007/s10519-012-9581-7

Neijts M, Dongen J van, Kluft C, Boomsma DI, Willemsen G, Geus EJC de. Genetic Architecture of the Pro-Inflammatory State in an Extended Twin-Family Design. Twin Research and Human Genetics. 2013;16(05):931-940
DOI: 10.1017/thg.2013.58

Ordonana JR, Bartels M, Boomsma DI, Cella D, Mosing M, Oliveira JR, Patrick DL, Veenhoven R, Wagner GG, Sprangers MAG, The GENEQOL Consortium. Biological pathways and genetic mechanisms involved in social functioning. Quality of Life Research. 2013;22(6):1189-1200
DOI: 10.1007/s11136-012-0277-5

Peyrot WJ, Middeldorp CM, R Jansen CM, Smit JH, Geus EJC de, Hottenga JJ, Willemsen G, Vink JM, Virding S, Barragan I, Ingelman-Sundberg M, Sim SC, Boomsma DI, Penninx BWJH. Strong effects of environmental factors on prevalence and course of major depressive disorder are not moderated by 5-HTTLPR polymorphisms in a large Dutch sample. Journal of Affective Disorders. 2013;146(1):91-99, Open Access
DOI: 10.1016/j.jad.2012.08.044

Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, DIAGRAM Consortium, MAGIC Investigators, Hottenga JJ, Penninx BWJH, Boomsma DI, Stefansson K, Duijn CM van, Abecasis GR, McCarthy MI, Hirschhorn JN, Qi L, Loos RJF, Lindgren CM, North KE, Heid IM, others. Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits. PLOS Genetics. 2013;9(6):e1003500, Open Access
DOI: 10.1371/journal.pgen.1003500
Supplementary Materials (zip file)

Revez JA, Bain L, Chapman B, Powell JE, Jansen R, Duffy DL, Tung JY, AAGC Collaborators, Penninx BWJH, Visscher PM, Geus EJC de, Boomsma DI, Hinds DA, Martin NG, Montgomery GW, Ferreira MAR. A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk. Genes and Immunity. 2013;14(7):441-446
DOI: 10.1038/gene.2013.38
Supplementary Materials (zip file)

Rietveld CA, Cesarini D, Benjamin DJ, Koellinger PD, Neve JE de, Tiemeier H, Johannesson M, Magnusson PKE, Pedersen NL, Krueger RF, Bartels M. Molecular genetics and subjective well-being. Proceedings of the National Academy of Sciences of the United States of America. 2013;110(24):9692-9697
DOI: 10.1073/pnas.1222171110
Supplementary Materials (zip file)

Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra H-J, Shakhbazov K, Abdellaoui A, Agrawal A, Rizzi TS, Boomsma DI, Hottenga JJ, Penninx BWJH, Willemsen G, Meyer MN, Posthuma D, Thurik AR, Timpson NJ, Uitterlinden AG, Duijn CM van, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD, others. GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment. Science. 2013;340(6139):1467-1471
DOI: 10.1126/science.1235488
Supplementary Materials (zip file)

Sabater-Lleal M, Huang J, Chasman DI, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Hottenga JJ, Dongen J van, Willemsen G, Boomsma DI, Geus EJC de, Watkins H, Samani NJ, Wallaschofski H, Smith NL, Trégouët D, Ridker P, Tang W, Strachan DP, Hamsten A, O'Donnell CJ, others. Multiethnic Meta-Analysis of Genome-Wide Association Studies in Over 100,000 Subjects Identifies 23 Fibrinogen-Associated Loci but no Strong Evidence of a Causal Association between Circulating Fibrinogen and Cardiovascular Disease. Circulation. 2013;128(12):1310-1324, Open Access
DOI: 10.1161/CIRCULATIONAHA.113.002251
Supplementary Materials (zip file)

Schork AJ, Thompson WK, Pham P, Torkamani A, Cooper Roddey J, Sullivan PF, Kelsoe JR, O’Donovan MC, Furberg H, Boomsma DI, Geus EJC de, Penninx BWJH, Posthuma D, Vink JM, Willemsen G, Schork NJ, Andreassen OA, Dale AM, others. All SNPs Are Not Created Equal: Genome-Wide Association Studies Reveal a Consistent Pattern of Enrichment among Functionally Annotated SNPs. PLOS Genetics. 2013;9(4):e1003449, Open Access
DOI: 10.1371/journal.pgen.1003449
Supplementary Materials (zip file)

Schutte NM, Hansell NK, Geus EJC de, Martin NG, Wright MJ, Smit DJA. Heritability of Resting State EEG Functional Connectivity Patterns. Twin Research and Human Genetics. 2013;16(05):962-969
DOI: 10.1017/thg.2013.55
Supplementary Materials (zip file)

Slof-Op’t Landt MCT, Bartels M, Middeldorp CM, Beijsterveldt CEM van, Slagboom PE, Boomsma DI, Furth EF van, Meulenbelt I. Genetic Variation at the TPH2 Gene Influences Impulsivity in Addition to Eating Disorders. Behavior Genetics. 2013;43(1):24-33
DOI: 10.1007/s10519-012-9569-3
Supplementary Materials (zip file)

Soelen ILC van, Brouwer RM, Baal GCM van, Schnack HG, Peper JS, Chen L, Kahn RS, Boomsma DI, Hulshoff Pol HE. Heritability of Volumetric Brain Changes and Height in Children Entering Puberty. Human Brain Mapping. 2013;34(3):713-725, Open Access
DOI: 10.1002/hbm.21468

Stephens SH, Hartz SM, Hoft NR, Saccone NL, Corley RC, Hewitt JK, Hopfer CJ, Breslau N, Coon H, Chen X, Vink JM, Hottenga JJ, Willemsen G, Boomsma DI, Penninx BWJH, Heath AC, Johnson EO, Kaprio J, Madden PAF, Martin NG, Stevens VL, Weiss RB, Kraft P, Bierut LJ, Ehringer MA, many others. Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking. Genetic Epidemiology. 2013;37(8):846-859
DOI: 10.1002/gepi.21760
Supplementary Materials (zip file)

Stroom EMC van der, König TE, Vink JM, Boomsma DI, Lambalk CB. Ovarian Reserve and Anti-Mullerian Hormone (AMH) in Mothers of Dizygotic Twins. Twin Research and Human Genetics. 2013;16(2):634-638
DOI: 10.1017/thg.2013.4

Velde SJ te, Aa N van der, Boomsma DI, Someren EJW van, Geus EJC de, Brug J, Bartels M. Genetic and Environmental Influences on Individual Differences in Sleep Duration During Adolescence. Twin Research and Human Genetics. 2013;16(06):1015-1025
DOI: 10.1017/thg.2013.74
Supplementary Materials (zip file)

Verbeek EC, Bevova MR, Bochdanovits Z, Rizzu P, Bakker IMC, Uithuisje T, Geus EJC de, Smit JH, Penninx BWJH, Boomsma DI, Hoogendijk WJG, Heutink P. Resequencing Three Candidate Genes for Major Depressive Disorder in a Dutch Cohort. PLOS ONE. 2013;8(11):e79921, Open Access
DOI: 10.1371/journal.pone.0079921

Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hottenga JJ, Geus EJC de, Willemsen G, Boomsma DI, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E. Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts. PLOS Medicine. 2013;10(2):e1001383, Open Access
DOI: 10.1371/journal.pmed.1001383
Supplementary Materials (zip file)

Willemsen G, Vink JM, Abdellaoui A, Braber A den, Beek JHDA van, Draisma HHM, Dongen J van, Ent D van ‘t, Geels LM, Lien R van, Ligthart L, Kattenberg VM, Mbarek H, Moor MHM de, Neijts M, Pool R, Stroo N, Kluft C, Suchiman HED, Slagboom PE, Geus EJC de, Boomsma DI. The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection. Twin Research and Human Genetics. 2013;16(1):271-281
DOI: 10.1017/thg.2012.140

Ye K, Beekman M, Lameijer EW, Zhanga Y, Moed MH, Akker EB van den, Deelen J, Houwing-Duistermaat JJ, Kremer D, Yahya Anvar S, Westendorp RGJ, Hoen PAC ‘t, Dunnen J den, Ommen GJB van, Willemsen G, Pitts SJ, Cox DR, Ning Z, Boomsma DI, Slagboom PE, others. Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs. Twin Research and Human Genetics. 2013;16(06):1026-1032
DOI: 10.1017/thg.2013.73
Supplementary Materials (zip file)

Zhernakova DV, Klerk E de, Westra HJ, Mastrokolias A, Amini S, Ariyurek Y, Jansen R, Penninx BWJH, Hottenga JJ, Willemsen G, Geus EJC de, Boomsma DI, Veldink JH, Berg LH van den, Wijmenga C, Dunnen JT den, Ommen G-JB van, Hoen PAC ’t, Franke L. DeepSAGE Reveals Genetic Variants Associated with Alternative Polyadenylation and Expression of Coding and Non-coding Transcripts. PLOS Genetics. 2013;9(6):e1003594, Open Access
DOI: 10.1371/journal.pgen.1003594
Supplementary Materials (zip file)